Tobacco use is the cause of the most preventable cancer deaths, and in many countries, the leading cause of cancer death. Furthermore, it is a risk factor that is the most globalized, and as such it has elicited a global response through the World Health Organization (WHO).
The cornerstone of tobacco control policies is the WHO Framework Convention on Tobacco Control (FCTC), its Guidelines, and the Illicit Trade Protocol. The WHO FCTC is the only treaty negotiated under the auspices of the WHO, and includes 179 Parties.
The treaty entered into force in February 2005 and provides an internationally coordinated response to combating the tobacco epidemic with specific steps for governments addressing tobacco use. These include demand reduction measures such as adopting tax and price measures to reduce tobacco consumption; banning tobacco advertising, promotion, and sponsorship; creating smoke-free work and public spaces; placing health warnings on tobacco packages; and supply reduction measures such as combating the illicit trade in tobacco products.