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Cancer is the leading cause of premature death in North America. An estimated 2.1 million new cancer cases and 701,000 cancer deaths occur in North America each year. The region contributes almost twice the proportion of cases compared to deaths globally (13% versus 7%) in large part because of high1

The cancer community is united behind the common goal of advancing health equity in cancer control. Equity is at the forefront of the global cancer community’s efforts to work toward a world where we can greatly reduce the risk of cancer and ensure that those who have cancer have access1

Curbing the tobacco epidemic is a global health priority to reduce the burden of cancer and other chronic diseases. The World Health Organization Framework Convention on Tobacco Control, the first global public health treaty, entered into force in 2005 and developed a set of six key tobacco-control measures (MPOWER, Map1

Cancer survival statistics highlight the degree of health care equity, reflecting the effectiveness of health systems in detecting, diagnosing, and treating cancers. Despite advancements in diagnostics and treatment, substantial disparities persist in international cancer survival both between and within countries due to inequality in the dissemination of advancements in diagnostic1

Cancers occurring in childhood and adolescence differ markedly from adult cancers in terms of the magnitude of the burden and biologic characteristics. Worldwide, the average annual incidence among children aged less than 15 years is 150 cases per million people and among adolescents aged 15-19 years the average annual incidence1

Editors Ahmedin Jemal, DVM, PhD, American Cancer Society Hyuna Sung, PhD, American Cancer Society Kieran Kelly, MPH, American Cancer Society Isabelle Soerjomataram, MD, PhD, International Agency for Research on Cancer Freddie Bray, MSc, PhD, International Agency for Research on Cancer

Climate change impacts cancer control in multiple ways (Figure 11.1). First, human activities cause climate change and increase exposures to cancer-causing agents. For example, extraction, processing, and use of fossil fuels not only exacerbates the greenhouse effect but also increases the risk of certain cancers. There is a strong relationship1

Law can be a powerful tool to address the burden of cancer – particularly for long-term, systemic change and addressing the underlying inequities and social determinants of health. Law encompasses a wide range of national, subnational, and international instruments and practices, including legislation, regulation, court cases, international agreements, administrative instruments,1

Global collaborative partnerships accelerate efforts to bridge the research gap, particularly in the areas of prevention and implementation and knowledge translation, to improve cancer outcomes worldwide. Countries and world regions need cancer research tailored to their unique disease burden and knowledge gaps to improve population health. Knowledge created in cancer1

Ethanol – the primary form of alcohol in alcoholic beverages – is the most widely used psychoactive substance globally. In 2019, the average annual amount of pure alcohol consumed per adult aged ≥15 years ranged from <2.5 liters in some countries in Africa, the Middle East, and Southeast Asia to1