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The Cancer Atlas aims to open readers’ eyes to the global scale and impact of cancer, covering the extent and magnitude of the disease, the major causes, and the different ways the disease can be prevented and treated. As with previous editions, this fourth edition of The Cancer Atlas is1

The continuing and escalating global fight against cancer demands new tools and the latest available data and trends. The Cancer Atlas website and The Cancer Atlas, Fourth Edition book – produced by the American Cancer Society and the International Agency for Research on Cancer – provide a comprehensive global overview1

Costs of new cancer treatments have grown exponentially and patients are treated longer with more agents, increasing the economic burden for patients and families, health care systems, and countries. The economic burden of cancer also includes indirect costs, measured as productivity losses from cancer morbidity and premature mortality, and productivity1

The delivery of high-quality, patient-centered cancer care requires capacity across multiple domains (infrastructure, staffing, resources, research, and data management systems) and multidisciplinary collaboration among health care centers, governments, nongovernmental organizations, and the international community. There remain unmet needs across the main modalities of cancer treatment in many areas of the1

Global cancer control requires a coordinated response from national governments, researchers, funders, practitioners, advocates, patients, and international organizations. Multiple high-level resolutions have called for reduced cancer mortality, but work remains to meet targets and understand what approaches work best, especially in low- and middle-income countries (LMICs), where burden is increasing.1

What started with one person in the US in 1985 to raise money and awareness has become a true global movement against cancer, uniting people in 35 countries (Figure 44.1) to do what no one country or organization can do alone: build a world free from cancer. Across the globe,1

Tobacco products cause at least 17 forms of cancer, and are collectively responsible for over 2 million cancer deaths per year (Figure 4.1).

At the American Cancer Society, we often celebrate the extraordinary progress we have made to reduce the death and suffering from cancer, driven by dramatic changes in the use of combustible tobacco, strategies to detect cancer earlier, the explosion of new therapeutics, and a greater focus on survivorship. In fact,1

Liver cancer is the sixth most frequently occurring cancer in the world, but due to the poor prognosis associated with the disease, it is the third largest contributor to cancer mortality, with an estimated 870,000 cases and 760,000 deaths in 2022 (Map 18.1).