"American"

Editors Ahmedin Jemal, DVM, PhD, American Cancer Society Hyuna Sung, PhD, American Cancer Society Kieran Kelly, MPH, American Cancer Society Isabelle Soerjomataram, MD, PhD, International Agency for Research on Cancer Freddie Bray, MSc, PhD, International Agency for Research on Cancer

This World Wide Web site with its home page in the domain “cancer.org” (the “Website”) is a complimentary information service offered by the American Cancer Society, Inc. (“ACS”) at no charge to users of the World Wide Web, with the express condition that these users agree to be bound by1

Cancer is the leading cause of premature death in North America. An estimated 2.1 million new cancer cases and 701,000 cancer deaths occur in North America each year. The region contributes almost twice the proportion of cases compared to deaths globally (13% versus 7%) in large part because of high1

At the American Cancer Society, we often celebrate the extraordinary progress we have made to reduce the death and suffering from cancer, driven by dramatic changes in the use of combustible tobacco, strategies to detect cancer earlier, the explosion of new therapeutics, and a greater focus on survivorship. In fact,1

Excess body fatness – overweight and obesity – has been linked to at least 13 types of cancer. Overall, approximately 4.5% of all cancer deaths globally are attributable to excess body fatness, varying from <1% in low-income countries to 7-8% in some high-income countries. The proportion of deaths linked to1

Climate change impacts cancer control in multiple ways (Figure 11.1). First, human activities cause climate change and increase exposures to cancer-causing agents. For example, extraction, processing, and use of fossil fuels not only exacerbates the greenhouse effect but also increases the risk of certain cancers. There is a strong relationship1

Colorectal cancer is the second leading cause of cancer death worldwide, with an estimated 1.9 million new cases and 900,000 deaths. Incidence rates range from <5 per 100,000 in Cape Verde, Sierra Leone, and India to >45 per 100,000 in Denmark and Norway (Map 16.1) and are strongly correlated with1

Global cancer control requires a coordinated response from national governments, researchers, funders, practitioners, advocates, patients, and international organizations. Multiple high-level resolutions have called for reduced cancer mortality, but work remains to meet targets and understand what approaches work best, especially in low- and middle-income countries (LMICs), where burden is increasing.1

The continuing and escalating global fight against cancer demands new tools and the latest available data and trends. The Cancer Atlas website and The Cancer Atlas, Fourth Edition book – produced by the American Cancer Society and the International Agency for Research on Cancer – provide a comprehensive global overview1